Polycystic Kidney Disease

“Polycystic kidney disease” or “PKD” is a disease that is inherited and causes the development of multiple non-cancerous cysts that can occur throughout the body but primarily develop in the kidneys. These cysts can cause the kidneys to become extremely enlarged and cause permanent scarring of the normal tissues of the kidneys to occur resulting in the impairment of kidney functioning.

This disease varies greatly with its severity as some individuals can have this disease for many years and not even be aware of it due to a lack of symptoms, IgA nephropathy research while others can experience symptoms that are severe including a significant loss in kidney functioning as well as total kidney failure.

The Causes and Symptoms of PKD

There are two types of polycystic kidney disease of which both are caused genetic abnormalities that are inherited. The primary differences between the two types of this disease are the genetic defects that caused them. “Autosomal dominant polycystic kidney disease” or (“ADPKD”) is the most common form of this disease and is primarily diagnosed in adults who are thirty to forty years of age; however, it can occur in children as well.

A child has a fifty percent chance of inheriting ADPKD when one parent has this disease. The other form of PKD is called “Autosomal recessive polycystic kidney disease” or “ARPKD” and is seen less commonly than ADPKD as both parents of a child must have the abnormal gene that causes this disease.

When both parents have this defective gene, there is a twenty five percent chance that there child will develop this condition. ARPKD is most commonly diagnosed at birth, however, it can be diagnosed later on during childhood or when the child has reached the age of adolescence. The symptoms of this disease may include:

• Hypertension (high blood pressure)

• The abdomen may increase in size or become enlarged.

• Frequent urination

• Blood may appear in the urine

• An individual may experience the development of kidney stones.

• Infection may occur within the urinary tract or the kidneys.

• Pain may occur in the back in the area of the kidneys due to their enlargement.

• Frequent headaches

• Kidney failure (end-stage renal disease)

Treatment for PKD

Because of the fact that there is no cure for PKD, treatment for polycystic kidney disease typically consists of treating the symptoms or complications that can occur from this condition. High blood pressure is a common occurrence among patients who develop kidney problems; therefore,  IgA nephropathy cure medications may be prescribed for controlling blood pressure.

Many individuals experience chronic pain due to their condition and mild to moderate pain may be controlled by over-the-counter medications, however, in more severe cases a physician may recommend the removal of larger cysts by a surgical procedure to relieve the pain and pressure that can be caused.

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